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Cheryl Corcoran, MD

Dr. Corcoran received her MD from Harvard Medical School. She completed her internship and residency in adult psychiatry at The Cambridge Health Alliance, a research fellowship in Schizophrenia Research at Columbia University, and a master’s degree in biostatistics at the Mailman School of Public Health. She is currently associate professor of psychiatry and program leader in psychosis risk at the Icahn School of Medicine at Mount Sinai.

Dr. Corcoran has research funding to study disturbances in sensory processing, language, and social cognition across stages of schizophrenia using MRI, EEG, and automated natural language processing analysis to measure semantic coherence and syntactic complexity. She has used non-invasive brain stimulation for cognitive mapping and to identify targets and circuits for therapeutic neurostimulation. Dr. Corcoran has also studied the role of stress and drug use in onset and symptom expression in schizophrenia, as well as stigma and paths to prevention and recovery. Her current research focuses on risk states and identifying brain mechanisms that underlie language disturbance and emotion recognition deficits in this population.


Research Interests

Schizophrenia, psychosis, language, artificial intelligence, risk, social cognition, stigma, non-invasive brain stimulation


Grants

Using the RDOC Approach to Understand Thought Disorder: A Linguistic Corpus-Based Approach (2018-2021)

Role: Principal investigator. Funding source: NIMH.


Thought Disorder and Social Cognition in Clinical Risk States for Schizophrenia (2017-2021)

Role: Principal investigator. Funding source: NIMH.


Automated Linguistic Analyses of Semantics And Syntax in Speech Output in the Psychosis Prodrome: A Novel Paradigm to Evaluate Subtle Thought Disorder (2016-2018)  

Role: Principal investigator. Funding source: NIMH.


Olfaction in the Psychosis Prodrome: Behavioral and ERP Measures (2009-2012)

Role: Principal investigator. Funding source: NIMH.


Schizophrenia Risk to Onset: Neurobiology and Prevention (2004-2009)

Role: Principal investigator. Funding source: NIMH.


In the News

Computer-Based Analysis of Language May Predict Psychosis Onset (Healio Psychiatric Annals, January 2018)

Speech Analysis Software Predicted Psychosis in At-Risk Patients With up to 83 Percent Accuracy (Science Daily, January 2018)


Presentations and Media Appearances


Publications (Selected)

A full list of Dr. Corcoran’s publications can be found here.

Martinez A, Gaspar PA, Hillyard SA, Andersen SK, Lopez-Calderon J, Corcoran CM, Javitt DC. Impaired motion processing in schizophrenia and the attenuated psychosis syndrome: etiological and clinical implications. American Journal of Psychiatry, 2018.  

Corcoran CM, Carrillo F, Fernandez-Slezak D, Bedi G, Klim C, Javitt DC, Bearden CE, Cecchi GA. Prediction of psychosis across protocols and risk cohorts using automated language analysis. World Psychiatry, 2018.

Bedi G, Carrillo F, Cecchi GA, Fernandez Sleza D, Sigman M, Mota NB, Ribeiro S, Javitt DC, Copelli M, Corcoran CM. Automated analysis of free speech predicts psychosis onset in high-risk youths. NPJ Schizophrenia, 2015.

Corcoran CM, Keilp JG, Kayser J, Klim C, Butler PD, Bruder GE, Gur RC, Javitt DC. Emotion recognition deficits as predictors of transition in individuals at clinical high risk for schizophrenia: a neurodevelopmental perspective. Psychological Medicine, 2015.  

DeVylder J, Muchomba F, Gill K, Ben-David S, Walder D, Malaspina D, Corcoran C. Symptom trajectories and psychosis onset in a clinical high-risk cohort: The relevance of subthreshold thought disorder. Schizophrenia Research, 2014.

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