VISN 6 > Research > Neuroimaging
Neuroimaging Research LabThe Neuroimaging Lab primary research area is focused on brain changes in posttraumatic stress disorder. Our second research area is focused on understanding changes in mild traumatic brain injury (mTBI) using diffusion imaging, resting-state functional MRI, and structural imaging to better understand the role of clinical symptoms and mechanism of injury. Our research in PTSD is focused on the role fear, threat, guilt and other emotions along with their interaction with cognitive function such as memory, attention, and executive function. Functional MRI employing cognitive challenge tasks, pharmacological challenges, emotion regulation strategies, as well as structural MRI, candidate gene, genome wide association studies (GWAS), and gene expression are converging methodologies for understanding mechanisms of PTSD. Our lab leads the international consortium workgroup on PTSD Neuroimaging within the Psychiatric Genetics Consortium. We have formulated a blue print to identify replicable genetic associations with brain measures in PTSD at a scope that is unprecedented in the field of traumatic stress. These efforts have triggered a renewed impetus and a sharpened focus on investigating structural and functional brain differences, their genetic determinants, environmental modulators, and investigating the genetic vulnerability to the effects of trauma and the onset of PTSD.
Rajendra A. Morey, M.D.